Antibody-Drug Conjugates Fueling Growth in the Global Antibody Drug Conjugates Market

 

Antibody-drug conjugates (ADCs) are advanced antibody-based therapeutics that deliver cytotoxic small-molecule drugs to tumor cells. They combine the targeting ability of antibodies with the cancer-killing ability of chemotherapy. By delivering highly potent anti-cancer drugs directly to tumor cells, ADCs help to kill cancer cells while reducing harmful off-target effects.

The global Antibody Drug Conjugates Market is estimated to be valued at US$ 5.38 Bn in 2023 and is expected to exhibit a CAGR of 14 % over the forecast period 2023 to 2030, as highlighted in a new report published by Coherent Market Insights.

Market key trends:
One of the key trends fueling growth in the Antibody Drug Conjugates market is the rising prevalence of cancer globally. According to World Health Organization (WHO), cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020. With the growing cancer burden, demand for targeted and effective therapeutics like ADCs is increasing substantially. Furthermore, increasing research activities focused on developing innovative ADCs against various cancer types is also boosting market growth. For instance, clinical trials evaluating efficacy of ADCs in treating lung cancer, breast cancer, etc. are ongoing which is expected to bring several new ADC drugs in the market in coming years.
Segment Analysis
The global antibody drug conjugates market is dominated by antibody-based conjugates segment due to advancements in linker and payload technologies. Antibody-based conjugates attach highly potent anti-cancer agents or small molecule anti-cancer "warheads" to monoclonal antibodies that bind to specific antigens on tumor cells, resulting in targeted delivery of the active agents to the tumor cells. This enables higher dosage of cytotoxic drugs to be delivered directly to the tumor while reducing systemic exposure and damage to normal cells.

Key Takeaways
The global antibody drug conjugates market is expected to witness high growth, exhibiting 14% CAGR over the forecast period, due to increasing prevalence of cancer worldwide.

Regional analysis
North America is expected to dominate the global antibody drug conjugates market owing to increasing Research & Development activities carried out by key players, rising awareness among oncologists about ADC therapeutics, and availability of supportive reimbursement policies in the region.

Key players
Key players operating in the antibody drug conjugates market are AstraZeneca PLC, Daiichi Sankyo Company, Limited, Novasep, ADC Therapeutics SA, Alentis Therapeutics AG, F. Hoffmann-La Roche, Gilead Sciences, Inc., AbbVie Inc., Biosion USA, Inc., Astellas Pharma Inc., Duality Biologics (Suzhou) Co. Ltd., BioNTech SE, LaNova Medicines Ltd., Bliss Biopharmaceutical, Eisai Co., Ltd., ProfoundBio, Pfizer, Inc., ImmunoGen Inc., Mersana Therapeutics Inc., Sorrento Therapeutics Inc., Oxford BioTherapeutics Ltd, and Takeda Pharmaceutical Company Ltd.

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