The global Amyotrophic Lateral Sclerosis Treatment Market Growth Accelerated by Innovative Clinical Trials


 Amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig's disease, is a neurodegenerative disease that affects nerve cells in the brain and spinal cord. The progressive degeneration of motor neurons results in weakness and ultimately paralysis in the muscles of voluntary movement. Drugs currently approved for the treatment of ALS only slow down progression of symptoms and extend survival by a few months.

The global Amyotrophic Lateral Sclerosis Treatment Market is estimated to be valued at US$ 692.77 Mn in 2023 and is expected to exhibit a CAGR of 4.6 % over the forecast period 2023-2030, as highlighted in a new report published by Coherent Market Insights.

Market key trends:

Innovative clinical trials evaluating the safety and efficacy of new drugs and therapeutic approaches are fueling growth of the ALS treatment market. For instance, Apotex Inc. is evaluating APX3330, an antioxidant inflammation modulator, in phase 2 clinical trials for the treatment of ALS. Other promising drugs in clinical trials include Orphazyme's arimoclomol and BrainStorm Cell Limited’s autologous neural stem cell product NurOwn. As there is currently no cure for ALS, an effective novel therapy receiving regulatory approval would capture a significant market share and accelerate overall industry growth. Advances in understanding the molecular pathways involved in ALS pathogenesis are also guiding development of new targeted therapies with the potential to slow or stop progression of the disease.


Segment Analysis

The global Amyotrophic Lateral Sclerosis Treatment Market is dominated by the drug therapeutics segment, which holds over 60% share of the overall market. Being a neurological disorder with no known cure, drugs targeting symptoms management hold utmost importance. Oral drugs currently account for the largest share as they offer convenience of administration over injectables.

Key Takeaways

The global Amyotrophic Lateral Sclerosis Treatment Market is expected to witness high growth over the forecast period of 2023 to 2030. The global Amyotrophic Lateral Sclerosis Treatment Market is estimated to be valued at US$ 692.77 Mn in 2023 and is expected to exhibit a CAGR of 4.6 % over the forecast period 2023-2030.

Regional Analysis

North America currently dominates the global market and is expected to retain its position over the coming years. Higher incidence rate of ALS as compared to other regions drives the market growth. Additionally, presence of majority key players and early adoption of advanced treatment options support the market growth in the region. Europe holds the second largest share due to growing rate of ALS cases and increasing initiatives by government and non-profit organizations for research.

Key Players

Key players operating in the Amyotrophic Lateral Sclerosis Treatment Market are Orion Corporation, Bausch Health Companies Inc., CYTOKINETICS, INC., Aquestive Therapeutics, Inc., Sanofi, Covis Pharma, Sun Pharmaceuticals Industries Ltd, Mitsubishi Tanabe Pharma Corporation, BrainStorm Cell Limited, ViroMed Co., Ltd, Ionis Pharmaceuticals, Genervon Biopharmaceuticals, LLC, Biogen, Orphazyme A/S, Apotex Inc, Neuralstem, Inc., Implicit Bioscience, F. Hoffmann-La Roche Ltd, AB Science, ADVANZ PHARMA.

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