The global Bispecific Antibodies Market Growth Accelerated by Rapid Adoption of Therapies for Cancer Treatment


With advancements in recombinant DNA technology and monoclonal antibody production, bispecific antibodies have emerged as promising therapeutic agents for the treatment of various cancers and other diseases. Bispecific antibodies can simultaneously bind two different epitopes or two different antigens, which may include binding a tumor antigen and a T-cell engaging antigen. This enables retargeting of T-cells to tumor cells with high specificity. As a result, bispecific antibodies provide better efficacy outcomes than conventional monoclonal antibodies in cancer immunotherapy.

The global Bispecific Antibodies Market is estimated to be valued at US$ 41.08 Mn in 2023 and is expected to exhibit a CAGR of 29% over the forecast period 2023 to 2030, as highlighted in a new report published by Coherent Market Insights.

Market key trends:
The rapid adoption of bispecific antibodies for cancer treatment has been a major market trend over the past few years. The ability of bispecific antibodies to recruit and activate T cells specifically at tumor sites provides more targeted cancer immunotherapy with improved survival outcomes. Several late-stage clinical trials evaluating the efficacy of bispecific antibodies in different cancer types such as leukemia, myeloma, lung cancer and others have shown promising results. This has accelerated their adoption among healthcare professionals and increased investment in the development of next-generation bispecific platforms to cater to the growing demand.
Segment Analysis

The global bispecific antibodies market can be segmented based on product, application, end-user, and geography. By product, the bispecific antibody segment dominated the market in 2022. Bispecific antibodies have a property of simultaneously binding to two different antigens. This property allows them to bring the distinct binding entities into close proximity, which ultimately helps triggering of novel biological responses. This has elevated their demand over other antibody formats.

Key Takeaways

The global bispecific antibodies market is expected to witness high growth over the forecast period. Recent approvals and ongoing clinical trials for novel bispecific antibodies will continue to drive the market in the coming years. The global Bispecific Antibodies Market is estimated to be valued at US$ 41.08 Mn in 2023 and is expected to exhibit a CAGR of 29% over the forecast period 2023 to 2030.

North America currently dominates the global bispecific antibodies market and is expected to continue its dominance over the forecast period. This is attributed to the growing incidences of cancer and autoimmune diseases in the region coupled with rising healthcare spending. The presence of major players and continuous research and development activities to develop innovative antibody therapeutics will further aid in North America's market growth.

Key players

Key players operating in the bispecific antibodies market are Amgen, Inc., Bayer AG, ImmunGene, Inc., Immunocore Limited, Merck & Co., Inc., Novartis AG, Pfizer, Inc., and F. Hoffmann-La Roche AG. Amgen Inc.'s bispecific antibody, Blincyto (blinatumomab), is one of the leading products in the market indicated for treating acute lymphoblastic leukemia. Merck & Co., Inc. recently received FDA approval for its bispecific antibody, Bavencio (avelumab), for treating metastatic Merkel cell carcinoma.

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